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PROJECT TOPIC:  PHYTOCHEMICAL ANALYSIS AND THE ANTI-INFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF CRATEVA ADANSONII
Department:  Bio Chemistry
AMOUNT:  10,000
FORMAT:   MS WORD
PAGES:  70
 
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ABSTRACT

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atherosclerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research, attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti-inflammatory drugs.
Anti-inflammation was carried out using 11 rats. That was divided into three groups of four rats each. Group 1 and 2 served as the positive and negative control respectively. Groups 3 and 4 received 200mg/kg b.w and 600mg/kg b.w. of the extracts respectively. However, it was discovered that the stem bark of crataeva Adansonii showed greater significance anti-inflammatory activity when compared with the standard.

CHAPTER ONE

1.0 INTRODUCTION

Anti inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti –inflammatory drugs make up about half of analgesics, reducing pain by inhibiting inflammation as opposed to opioids, which affect the central nervous system published by Artemis Morris, molly Rossiter.
Inflammation (Latin, inflammo, “I ignite, set alight”) is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The classical signs of inflammation are pain, heat, redness, swelling and loss of function by Dr Weil. Inflammation is a protective attempt by the organism to remove the injurious stimuli and initiate the healing process.
Inflammation is not a synonym for infection, even in cases where inflammation is caused by infection. Although infection is caused by a microorganism, and organism pathogen.
Inflammation is a stereotyped response and is considered as a mechanism of innate immunity by Dr. Weil.

 

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